SPRAVATO® (esketamine)

Welcome to the SPRAVATO® channel. SPRAVATO® is the only FDA-approved nasal spray, taken with or without an antidepressant, for treatment-resistant depression in adults. SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine. It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®. It is not known if SPRAVATO® is safe and effective in children. Visit SPRAVATO.com to learn more. Please see Important Safety Information, including Boxed WARNINGS, throughout and at the end of videos and the full Prescribing Information, including Boxed WARNINGS in the links below. ©Johnson & Johnson and its affiliates 2025 12/25 cp-457382v8